Lytle Creek is in southwestern San Bernardino County in the eastern San Gabriel Mountains. During the 1890s there was an appreciable amount of placer mining here. Operations extended from near the mouth of the canyon to near its headwaters on the east slope of Mt. San Antonio (Mt. Baldy). Work was done both by hydraulicking and hand methods. The stream was named for Andrew Lytle, a member of the Mormon colony that settled in San Bernardino in 1851.